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Du et al. (2018) "Low Concentrations of Caffeine and Its Analogs Extend the Lifespan of " Front Aging Neurosci 10:211 (PubMed)

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  2. Caffeine demonstrated an avg lifespan change of 15.39 in Caenorhabditis elegans DrugAge
  3. 1-methylxanthine demonstrated an avg lifespan change of 5.05 in Caenorhabditis elegans DrugAge
  4. 3-methylxanthine demonstrated an avg lifespan change of 0.93 in Caenorhabditis elegans DrugAge
  5. 7-methylxanthine demonstrated an avg lifespan change of 8.41 in Caenorhabditis elegans DrugAge
  6. 1,3-dimemethyl Xan demonstrated an avg lifespan change of 5.54 in Caenorhabditis elegans DrugAge
  7. 1,7-dimethylxanthine demonstrated an avg lifespan change of 14.75 in Caenorhabditis elegans DrugAge
  8. 3,7-dimethylxanthine demonstrated an avg lifespan change of -0.84 in Caenorhabditis elegans DrugAge