Entries for the source GenAge: Ageing-Associated Genes in Model Organisms (710)

1838: Cao et al. (2006) "ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency." EMBO J. 25(10):2167-2177 (PubMed)

3478: Carrano et al. (2014) "A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans." Nat Commun 5:3772 (PubMed)

2572: Carrano et al. (2009) "A conserved ubiquitination pathway determines longevity in response to diet restriction." Nature 460(7253):396-399 (PubMed)

2178: Casellas and Medrano (2008) "Lack of Socs2 expression reduces lifespan in high-growth mice." Age (Dordr) 30(4):245-249 (PubMed)

4394: Cattie et al. (2016) "Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans." PLoS Genet. 12(9):e1006326 (PubMed)

2379: Chamberlain et al. (2007) "Dystrophin-deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma." FASEB J. 21(9):2195-2204 (PubMed)

3471: Chamoli et al. (2014) "A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans." Aging Cell 13(4):641-655 (PubMed)

2427: Château et al. (2010) "Klotho interferes with a novel FGF-signalling pathway and insulin/Igf-like signalling to improve longevity and stress resistance in Caenorhabditis elegans." Aging (Albany NY) 2(9):567-581 (PubMed)

211: Chavous et al. (2001) "Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase." Proc. Natl. Acad. Sci. U.S.A. 98(26):14814-14818 (PubMed)

4430: Chawla et al. (2016) "A let-7-to-miR-125 MicroRNA Switch Regulates Neuronal Integrity and Lifespan in Drosophila." PLoS Genet. 12(8):e1006247 (PubMed)

2246: Chen et al. (2007) "Longevity determined by developmental arrest genes in Caenorhabditis elegans." Aging Cell 6(4):525-533 (PubMed)

3246: Chen et al. (2011) "Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability." BMC Cancer 11:199 (PubMed)

2153: Chen et al. (2009) "Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice." Genes Dev. 23(10):1183-1194 (PubMed)

3497: Chen et al. (2009) "The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span." Proc. Natl. Acad. Sci. U.S.A. 106(5):1496-1501 (PubMed)

2374: Chen et al. (2006) "Ump1 extends yeast lifespan and enhances viability during oxidative stress: central role for the proteasome?" Free Radic. Biol. Med. 40(1):120-126 (PubMed)

2571: Chen et al. (2009) "HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans." PLoS Genet. 5(5):e1000486 (PubMed)

3489: Chen et al. (2013) "Identification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants." PLoS ONE 8(7):e69084 (PubMed)

980: Cheng et al. (2003) "Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice." Proc. Natl. Acad. Sci. U.S.A. 100(19):10794-10799 (PubMed)

2456: Cheung and Dennis (2007) "Mgat5 and Pten interact to regulate cell growth and polarity." Glycobiology 17(7):767-773 (PubMed)

2320: Cheung et al. (2007) "Metabolic homeostasis and tissue renewal are dependent on beta1,6GlcNAc-branched N-glycans." Glycobiology 17(8):828-837 (PubMed)